
why biostimulators like radiesse and sculptra are the future of cosmetic medicine
Something has changed in cosmetic medicine over the past few years, and biostimulators are a big part of it. Where clients once came in mainly asking for fillers, we now see growing interest in treatments that encourage the body to repair itself. Biostimulators such as Radiesse, Sculptra and Julaïne are quickly growing in popularity. Treatments based on the body’s own materials, such as PRP, PRF and exosomes, are being used more and more too.
At UMA Clinic in Amsterdam, cosmetic doctor Jani van Loghem (KNMG) sees this shift in practice every day. More and more clients are choosing treatments that support the skin’s natural ability to renew itself.
“This movement fits perfectly with how I’ve looked at cosmetic medicine for years. I’ve always been interested in treatments that don’t just add something, but that encourage the body to become active again on its own.”
what are biostimulators?
Well-known biostimulators include Radiesse, Novuma, Sculptra and Julaïne. These treatments are used to stimulate your natural collagen production and can help give you firmer skin, more elasticity and a subtle rejuvenation of the face.
According to Jani, cosmetic medicine is going through an important shift.
“Ageing isn’t just about losing volume. We also lose collagen, elasticity and skin quality. If you only add volume, you’re really only treating part of the problem.”
That’s exactly why the regenerative side appeals to him so much.
“Biostimulators give the body a nudge to make its own collagen. You’re supporting natural processes. That often leads to a very subtle, but incredibly beautiful result.”
how do radiesse and sculptra stimulate collagen?
Biostimulators are injectable products that encourage the body to make new collagen.
“They activate the body’s ability to repair itself. That makes them fundamentally different from traditional fillers, where you only add volume.”
That’s why the result usually builds gradually.
“Clients usually don’t notice a big difference overnight. It’s exactly that slow process of improvement that makes it so interesting.”
the body knows more than we think
Talk to Jani for a few minutes and you’ll soon notice that his fascination with regeneration runs deep.
And that’s no coincidence. His grandfather founded an entirely new medical specialty within allergology. His grandmother was a pioneer in genetics and immunology.
“They taught me to stay curious. To always ask: why does this happen? And how can we understand it better?”
He sees that same curiosity in cosmetic medicine.
“We’re discovering more and more about the way the body can repair itself. I find that incredibly fascinating. It shows that the body often has far more potential than we thought for years.”
safety starts with understanding
Regenerative treatments are getting a lot of attention, but Jani also warns against making them sound too simple.
“No treatment is a miracle cure. Success depends on the right indication, the right technique and, above all, an understanding of the underlying anatomy.”
It’s also the reason he trains doctors and healthcare professionals around the world.
“Injecting is simple. But I want doctors to understand why a treatment works, and why one approach is safer than another.”
For him, safety doesn’t start with a protocol.
“Safety starts with insight.”
why more and more clients are choosing regenerative treatments
According to Jani, many people feel drawn to treatments that support natural processes.
“Clients often don’t want to look different. They want to look rested. Fresher. More vital. They want to recognise themselves when they look in the mirror.”
That makes regenerative treatments especially suitable for people looking for subtle, natural-looking results.
“The most beautiful results are often the ones nobody can quite put their finger on. People don’t say: ‘Have you had something done?’ They say: ‘You look great.’”
the future of cosmetic medicine
So how does Jani see the future?
“We’ll understand better and better how to support the body in repair and rejuvenation. That doesn’t mean fillers will disappear. Quite the opposite. But regenerative treatments add a really important new chapter to our field.”
For him, though, the essence stays the same.
“Whatever technique or product you use, in the end it’s about the person sitting in front of you. That’s where it starts. And that’s where it ends.”

Wondering which treatment suits your skin best? Book a complimentary consultation at UMA Clinic in Amsterdam and get personal advice from cosmetic doctor Jani van Loghem (KNMG).
about Jani van Loghem
Dr Jani van Loghem is a cosmetic doctor (KNMG) and the founder of UMA Clinic in Amsterdam. He’s an international trainer and speaker in injectables, anatomy and regenerative medicine, and earned his PhD on improving safety in filler treatments. Through UMA Academy, Jani trains doctors from the Netherlands and abroad in injection techniques and advanced aesthetic treatments. In Amsterdam, he welcomes specialists from all over the world for hands-on training and live demonstrations.
frequently asked questions about biostimulators
A filler adds volume straight away, right where it’s injected. A biostimulator encourages your skin to make new collagen of its own, so your skin quality improves gradually. Some products, such as Radiesse, do both.
Because your skin is making its own collagen, the result builds gradually. Most clients notice their skin looking firmer and fresher after a few weeks to months.
That depends on the product and on you. Results often stay visible for more than a year. During your consultation, your doctor will talk you through what you can expect.
Often one to three treatments, depending on the product, your skin and the result you’re after. Together with your doctor, you’ll create a personalised treatment plan.
Pricing depends on the product and the amount you need. Take a look at the uma clinic price list for current rates. During your complimentary consultation, we’ll give you a clear, upfront quote. No surprises.
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